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Arava (generic name: leflunomide; brand names include: Lefra / Cleft) is a disease-modifying antirheumatic drug (DMARD).
Arava is used for reducing signs and symptoms of rheumatoid arthritis and active psoriatic arthritis including joint tenderness, swelling, pain, and morning stiffness. It also helps reduce joint damage and improves physical functioning.
Arava is the only oral DMARD indicated to improve physical function.
Unlike many symptom relievers that only help relieve pain and swelling, Arava actually helps slow the progression of joint damage caused by rheumatoid arthritis.
Arava works by selectively interfering with the ability of white blood cells called lymphocytes to produce the disease response that ultimately leads to pain, inflammation and joint damage.